KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSH6
All Species:
20.61
Human Site:
T1344
Identified Species:
32.38
UniProt:
P52701
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52701
NP_000170.1
1360
152786
T1344
C
L
A
S
E
R
S
T
V
D
A
E
A
V
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113749
1360
152750
T1344
C
L
A
S
E
R
S
T
V
D
A
E
A
V
H
Dog
Lupus familis
XP_531814
1283
145094
T1267
C
L
A
S
E
R
S
T
V
D
A
E
A
V
P
Cat
Felis silvestris
Mouse
Mus musculus
P54276
1358
151058
T1342
C
L
A
T
E
K
P
T
I
N
G
E
A
I
H
Rat
Rattus norvegicus
XP_002726765
1361
151628
T1345
C
L
A
S
E
R
P
T
V
N
S
E
A
I
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419359
1466
164165
T1450
C
R
V
V
D
G
V
T
H
D
A
N
A
V
G
Frog
Xenopus laevis
NP_001089247
1340
149481
L1322
F
R
E
L
F
L
A
L
D
N
G
S
P
E
G
Zebra Danio
Brachydanio rerio
NP_878280
1369
153213
R1353
C
S
F
A
E
S
P
R
A
E
R
E
Q
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUM0
1190
133117
I1175
E
D
T
K
K
E
K
I
N
A
L
K
D
L
L
Honey Bee
Apis mellifera
XP_392346
1120
127429
L1105
R
K
H
F
F
I
T
L
C
K
A
N
G
S
T
Nematode Worm
Caenorhab. elegans
NP_491163
1186
133609
D1171
H
L
V
E
C
A
R
D
D
N
F
D
V
G
E
Sea Urchin
Strong. purpuratus
XP_797647
1335
149141
M1307
F
E
E
S
A
E
R
M
K
F
F
R
S
V
H
Poplar Tree
Populus trichocarpa
XP_002320307
1288
142120
G1270
L
S
G
H
K
S
A
G
I
D
I
S
S
V
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04716
1324
146779
S1303
V
A
S
D
S
D
Y
S
A
S
K
D
S
L
C
Baker's Yeast
Sacchar. cerevisiae
Q03834
1242
140062
R1227
N
Y
D
W
N
I
K
R
N
V
L
K
S
L
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.3
88.1
N.A.
85.8
86.4
N.A.
N.A.
64.2
66.5
60
N.A.
39
41.2
34.4
48.6
Protein Similarity:
100
N.A.
98.6
91.3
N.A.
92.1
92.8
N.A.
N.A.
75.4
79.9
74.9
N.A.
57.6
58
52.7
66.6
P-Site Identity:
100
N.A.
100
93.3
N.A.
53.3
73.3
N.A.
N.A.
40
0
20
N.A.
0
6.6
6.6
20
P-Site Similarity:
100
N.A.
100
93.3
N.A.
86.6
93.3
N.A.
N.A.
46.6
13.3
40
N.A.
20
13.3
20
26.6
Percent
Protein Identity:
36.1
N.A.
N.A.
33.2
29
N.A.
Protein Similarity:
52
N.A.
N.A.
51.4
49.1
N.A.
P-Site Identity:
13.3
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
40
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
34
7
7
7
14
0
14
7
34
0
40
0
0
% A
% Cys:
47
0
0
0
7
0
0
0
7
0
0
0
0
0
7
% C
% Asp:
0
7
7
7
7
7
0
7
14
34
0
14
7
0
0
% D
% Glu:
7
7
14
7
40
14
0
0
0
7
0
40
0
7
7
% E
% Phe:
14
0
7
7
14
0
0
0
0
7
14
0
0
0
7
% F
% Gly:
0
0
7
0
0
7
0
7
0
0
14
0
7
7
14
% G
% His:
7
0
7
7
0
0
0
0
7
0
0
0
0
0
34
% H
% Ile:
0
0
0
0
0
14
0
7
14
0
7
0
0
14
0
% I
% Lys:
0
7
0
7
14
7
14
0
7
7
7
14
0
0
0
% K
% Leu:
7
40
0
7
0
7
0
14
0
0
14
0
0
27
7
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
7
0
0
0
14
27
0
14
0
0
0
% N
% Pro:
0
0
0
0
0
0
20
0
0
0
0
0
7
0
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% Q
% Arg:
7
14
0
0
0
27
14
14
0
0
7
7
0
0
0
% R
% Ser:
0
14
7
34
7
14
20
7
0
7
7
14
27
7
0
% S
% Thr:
0
0
7
7
0
0
7
40
0
0
0
0
0
0
20
% T
% Val:
7
0
14
7
0
0
7
0
27
7
0
0
7
40
0
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _